How Long Does Upneeq Last?

If you're considering Upneeq (oxymetazoline hydrochloride ophthalmic solution), 0.1% for drooping eyelids, a common question is, "exactly how long does Upneeq last?" Understanding the duration of its effects can help you manage your expectations and incorporate it seamlessly into your daily routine. Upneeq, containing oxymetazoline hydrochloride, is designed to temporarily lift the upper eyelids. This lift typically lasts for several hours, providing a noticeable improvement in eyelid elevation. In clinical trials, the average lift was 1 mm, but results may vary.

Specifically, the effect of Upneeq is observed to last for up to 8 hours in many patients. This duration allows patients to experience the visual and cosmetic benefits of improved eyelid position for a significant portion of the day. The actual duration can vary from person to person, but generally, you can expect several hours of noticeable lift after each application. This makes Upneeq a practical option for daily use, especially for those seeking a non-invasive solution to mild to moderate acquired ptosis.

How Long Does Upneeq Take to Work?

Upneeq is formulated for rapid onset of action. Most users begin to see noticeable improvements in eyelid elevation within 15 minutes of application. This quick response allows for convenient use, even when preparing for social events or daily activities.

How Does Upneeq Work?

To understand how long the effect of Upneeq lasts, it is important to know how it works. Upneeq contains oxymetazoline hydrochloride, an alpha-adrenergic agonist. When applied, it stimulates the Müller’s muscle, which is responsible for lifting the upper eyelid. This stimulation causes the muscle to contract, resulting in a temporary lift of the eyelid.

This targeted action is what makes Upneeq effective in improving upper eyelid position. It addresses the underlying muscle function related to ptosis, providing a functional and cosmetic improvement without invasive procedures.

How Often Should I Use Upneeq?

Upneeq is a once-daily eye drop. . Applying one drop in each affected eye can provide the desired lift for several hours. Always follow the prescribed dosage and application instructions when using Upneeq. It is important to remember that Upneeq provides a temporary lift, and its effects will subside over time.

Is Upneeq Right for Me?

If you’re experiencing acquired ptosis, Upneeq may be a suitable option. However, it is important to consult with an health care professional to determine the best course of treatment for your specific needs. They can assess your condition and medical history, discuss potential benefits and risks, and provide personalized recommendations.

Upneeq is designed to temporarily lift the upper eyelids, improving visual field and cosmetic appearance. However, it is not a cure for ptosis and should be used as directed by a healthcare provider. The most common side effects of Upneeq® (occurring in 1–5% of patients) include eye inflammation, eye redness, dry eye, blurred vision, eye pain at time of use, eye irritation, and headache.

Take our Eyelid Height Questionnaire to help you determine if you might have droopy eyelids. You can use this self-assessment as a starting point to talk to your doctor about whether you might benefit from FDA-approved Upneeq eye drops.

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Upneeq is the only FDA-approved, prescription eye drop that lifts low-lying eyelids (acquired ptosis). Find out if Upneeq’s eye-opening benefits are right for you.

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IMPORTANT SAFETY INFORMATION

What is UPNEEQ?

UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is a prescription eyedrop used to treat acquired blepharoptosis (low-lying lids) in adults.

What warnings and precautions are associated with UPNEEQ?

Low-lying lids may be related to conditions such as stroke and/or brain aneurysm, Horner syndrome, myasthenia gravis, loss of the ability to move eye muscles, eye infection and eye tumors. Tell your doctor if you have any of these conditions.
UPNEEQ is a type of medication that may affect your blood pressure. If you have heart disease, uncontrolled high or low blood pressure, or feel faint at rest or when quickly standing up, you should call your doctor if your symptoms get worse.
Patients with reduced blood flow to the brain or heart, or patients who experience eye or mouth dryness due to an immune system disorder (Sjögren’s syndrome), should use care when taking UPNEEQ. Call your doctor immediately if you feel your symptoms may be getting worse.
UPNEEQ may increase the risk of eye pressure due to fluid buildup (angle-closure glaucoma) in patients with untreated narrow-angle glaucoma. Call your doctor immediately if you feel increased pressure in your eye after using UPNEEQ.
Do not let the tip of the UPNEEQ vial touch your eye or any other surface. This can help prevent eye injury or contamination. Each UPNEEQ vial is for one-time use and should be discarded after being used.

What are the most common side effects of UPNEEQ?

The most common adverse reactions with UPNEEQ (occurring in 1-5% of patients) were eye inflammation, eye redness, dry eye, blurred vision, eye pain at time of use, eye irritation, and headache.

What should my doctor know about before prescribing me UPNEEQ?

Your doctor should review your full medical history before prescribing UPNEEQ.
UPNEEQ belongs to a class of medication (alpha-adrenergic agonists) that may affect your blood pressure. Use UPNEEQ carefully if you currently take an alpha-adrenergic agonist medication to treat heart disease or an enlarged prostate. Patients taking beta-blockers, or other medications to treat hypertension or an abnormal heartbeat, should also be careful when using UPNEEQ.
Patients who use a certain class of antidepressant medication (monoamine oxidase inhibitors) should also be careful when using UPNEEQ, as it may affect the way your body absorbs the medication.

These are not all of the possible side effects of UPNEEQ. Tell your doctor if you have any side effect that bothers you or does not go away. Call your doctor for medical advice about side effects.
To report side effects or product complaints, contact RVL Pharmaceuticals at 1-877-482-3788. You may also report side effects to the FDA by calling 1-800-FDA-1088 or visit www.fda.gov/medwatch.
This is a summary of the most important safety information for UPNEEQ. For more in-depth safety information, please review the full Prescribing Information for UPNEEQ.